It can be done all-year round, although it is advisable to increase precautions at timeswhen sun exposure is not as intense or prolonged, such as winter and autumn. It ishighly recommendable to avoid intense and prolonged sun exposure, or extreme heatsources such as continuous baking/grilling, saunas, hot yoga, etc.

The mesoestetic® Cosmelan consists of an in-office protocol and a home routine, bothof which are necessary to achieve the best results possible in terms of antiaging anddepigmentation. The treatment's total duration is about 6 months.

The most meaningful change occurs a few weeks after the application of the mask inthe office and starting the home care. The texture of the skin improves, expression linesand dark spots are visibly reduced, but the process is not over as it includes not only acorrective phase but also a regulatory phase, meaning that results can be seen in thefirst weeks but are not final, so the continuous application is needed to ensureprogressive and accumulative effect.

Suspending the home treatment will be an incomplete treatment. This can eventuallylead to hyperpigmentation rebounding, Post inflammatory hyperpigmentation andincreased skin sensitivity/reactivity to environment. If the treatment needs to beresumed after stopping it, the case must be evaluated but it is highly possible it must berestarted completely.

There are some expected noticeable skin changes which could implicate the avoidanceof certain activities such as: waxing, swimming pools, saunas, hot yoga, excessiveoutdoor activities, prolonged exposure to heat sources and extreme sweating. Downtime is expected during the first weeks but may vary from case to case.

Cosmelan is not a once in a lifetime protocol. It can be repeated in the case ofreappearance of the pigmentation. To ensure long lasting results, the fulfillment of theprotocol is suggested, maintenance sessions can be performed and the use of melaninregulating products is recommended.

If Cosmelan has been performed in the past, a new evaluation of diagnosis is neededbefore deciding whether or not it shall be used again, or if a different protocol is needed.

Maintenance treatments are suggested using Mesopeel melanostop tranex, MesopeelMD Melanostop tranex and c.prof 210 depigmentation solution (ask your aestheticconsultant). The use of melanin controlling products such as Melan tran3x concentrateand Melan tran3x gel cream is strongly advised, as well as a proper SPF such as Melan130 pigment control or the Mesoprotech product that best suits patient’s skin type.

The formula has evolved integrating innovative active ingredients, increasing the scopeof patients now targeting aging, and simplifying home care protocol. However, the mainstructure of the product remains the same.

New ingredients have been added as well as our very own patented molecules,maintaining the core structure:

• Melaphenone (patent pending) for pigmentation and antiaging.
• Cosmesome (patent pending) encapsulated apegenina and floretina.
• Salicylic Acid
• Retynil Palmitate /Retinol
• Niacinamide
• Hesperidine
• Kojic Acid
• Ascorbic Acid
• Glabra root extract
• Rumex occidentalis
• Hexylresorcinol
• Idebenone
• Phytic Acid

As of now, there is no MD version. The formula is still considered medical grade.

Even though the application is not overly complex; it is crucial to have an accuratediagnosis of the pigmentation and a deep knowledge of melasma.

The results are more comprehensive as they include targeting intracellular,extracellular, and intercellular factors that affect processes of photoaging, intrinsicaging and hyperpigmentation.

Results may vary depending on the patient.

No. The exclusive combination of ingredients and the recently incorporated patentedactives are enough to effectively manage hyperpigmentation.

Cosmelan formula has been upgraded. The new formula contains actives like retinylpalmitate, melaphenone and Cosmesome (delivery technology) which are sufficient forit to be as effective.

Cosmelan results depend primarily on the following protocol and may vary from patientto patient.

Mechanisms of action of its components plus all laboratory research support theefficacy of the recently improved Cosmelan.

It is advisable and recommended.

Yes, it is optimized and simplified.

Results will always have an individual component corresponding to each patient. Thismethod now includes two patents and innovative active ingredients in its formula thatcontribute to treating not only hyperpigmentation but also aging. It is a morecomprehensive version.

As the #1 depigmenting treatment, we lead the way in controlling and reducing visibledark spots, so we prioritize innovation. Efficacy in the protocol, improved monitoring,reinforcement of anti-aging power related to melasma all lead to staying at the top.

Unfortunately, there are no exchanges.

Yes. Cosmelan has a dedicated area on our website with further information for you.

No, you will receive product credit.

The color of the products stays the same. Any change in color does not affect theeffectiveness or quality of the product.

Cosmelan is a two-phase protocol, including correction and regulation of the pigmentbut also an antiaging effect. To this matter, we can expect mild erythema, skin shedding,slight edema, tight/dry skin, and a tingly sensation during the initial applications. Pleaseadvise your patients to stick to the protocol as much as possible and avoid pulling theskin.

Cosmelan pack includes Cosmelan Home Pack which has Cosmelan 2, Melan recoveryand Melan 130 pigment control. These products are what is needed but you could add adermal cleanser such as Hydra cream fusion or Brightening foam. In specific cases, werecommend contacting your aesthetic consultant.

No. It is possible that patients will need to repurchase the home care products tocomplete their treatment.